Yazar "Alkan, M." için listeleme
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Does vitamin C prevent the effects of high dose dexmedetomidine on rat erythrocyte deformability?
Kurtipek, O.; Comu, F. M.; Ozturk, L.; Alkan, M.; Pampal, K.; Arslan, M. (Comenius Univ, 2012)Purpose: Dexmedetomidine is an anesthetic agent frequently used for sedation at the intensive care units and during general anesthesia. The purpose of our study was to investigate whether vitamin C prevents the effect of ... -
Effect of iloprost on erythrocyte deformability in rat's lower extremity undergoing an ischemia reperfusion injury
Arslan, M.; Donmez, T.; Erer, D.; Tatar, T.; Comu, F. M.; Alkan, M. (Comenius Univ, 2013)Aim: Ischemia reperfusion injury (I/R) in lower extremity is a frequent and important clinical phenomenon. The protective effect of iloprost on local and distant organ injury due to I/R has been well documented but its ... -
Effect of levosimendan on erythrocyte deformability during myocardial ischaemia-reperfusion injury
Arslan, M.; Comu, F. M.; Alkan, M.; Kiraz, H. A.; Kip, G.; Ozer, A.; Sivgin, V (Comenius Univ, 2015)Diabetes mellitus (DM) is a chronic metabolic disorder accompanied by an increase in oxidative stress. Ischaemia-reperfusion (IR) injury is a cascade of events initiated by tissue ischaemia. The cellular damage produced ... -
Effects of dexmedetomidine and thymoquinone on erythrocyte deformability in lower limb ischemia reperfusion injury in streptozotocin-induced diabetic rats
Ozer, A.; Comu, F. M.; Kucuk, A.; Kilic, Y.; Alkan, M.; Oktar, L.; Ozturk, L. (Comenius Univ, 2018)OBJECTIVE: In this study we aimed to evaluate the effect of dexmedetomidine and thymoquinone on erythrocyte deformability in lower limb ischaemia-reperfusion (IR) injury in streptozotocin-induced diabetic rats. MATERIAL ... -
Effects of intravenous ibuprofen and lornoxicam on erythrocyte deformability in rats undergoing hind limb ischemia reperfusion injury
Sivgin, V; Kucuk, A.; Comu, F. M.; Kosem, B.; Kartal, S.; Turgut, H. C.; Alkan, M. (Comenius Univ, 2016)BACKGROUNDAND AIM: Acute hind limb ischemia reperfusion (I/R) injury is a common consequence of abdominal aorta cross-clamping during aortic surgery. Erythrocyte deformability is affected by I/R process and may lead to ... -
The effects of low and high doses of sugammadex on kidney tissue in streptozotocin-induced diabetic rats
Kip, G.; Turgut, H. C.; Alkan, M.; Aydin, M. E.; Erbatur, M. E.; Kiraz, H. A.; Unal, Y. (Comenius Univ, 2015)BACKGROUND: Sugammadex is primarily excreted via renal route. We investigated effects of low and high doses of sugammadex (16 mg/kg versus 96 mg/kg) on renal tissue samples of streptozotocin-induced diabetic rats. MATERIAL ... -
The effects of propofol and memantine on erythrocyte deformability
Unal, Y.; Comu, F. M.; Emik, U.; Alkan, M.; Pampal, H. K.; Arslan, M. (Comenius Univ, 2014)Objective: Propofol is an intravenous general anesthetic with a primary hypnotic effect. Memantine is an NMDA receptor antagonist that has been shown to reverse changes in memory and synaptic plasticity in animal models. ... -
Investigation of the effects of propofol and vitamin C administration on erythrocyte deformability in rats with streptozotocin-induced diabetes mellitus
Comu, F. M.; Ozturk, L.; Alkan, M.; Pampal, K.; Arslan, M.; Isik, B.; Yilmaz, D. (Comenius Univ, 2014)Purpose: In the current study we aim to investigate the effects of vitamin C and profol on red blood cell deformability in diabetic rats Materials and methods: Twenty- eight Wistar Albino rats were included in the study ...